Table of Contents
- Introduction
- Criteria for Selecting Leading Supplement Manufacturers
- 1. Pharmavite (Nature Made)
- 2. Elysium Health
- Usana Health Sciences
- 4. NutraPak USA
- 5. Cavendish Nutrition
- 6. Brand International
- 7. HH Processors
- 8. ENZ Pharmtech (Global Reach)
- Summary Table
Introduction
In 2025, the U.S. supplement industry continues to flourish, supported by companies that champion quality, innovation, and regulatory compliance. From multivitamins and sports nutrition to niche nootropics, the demand for trusted, science-backed manufacturers is unprecedented. This guide highlights the top 8 supplement manufacturers in the USA, spotlighting their offerings, certifications, and unique strengths—a must-read for businesses seeking reliable contract or private-label partners.
Criteria for Selecting Leading Supplement Manufacturers
- Regulatory Compliance: Certifications including FDA cGMP, NSF, USP, ISO
- Product Range: Gummies, capsules, tablets, softgels, powders, liquids
- Manufacturing Capacity: From prototypes to large-scale production
- Market Reputation: Partnerships with top 500 companies or global brands
- Formulation Expertise: Ability to innovate and customize formulas
1. Pharmavite (Nature Made)
Pharmavite, the maker of Nature Made®, is one of America’s most trusted multivitamin brands . Operating multiple GMP-certified facilities across California and Alabama, Pharmavite offers everything from standard vitamins to specialized blends and gummy nutrients. Their Gummy Center of Excellence, opened in 2023, underscores their commitment to innovation in format and formulation .
2. Elysium Health
Elysium Health is known for pioneering high-tech nutraceutical products focused on longevity, such as Basis, Matter, and Vision . Founded in 2014 and backed by cutting-edge research, Elysium targets niche health sectors like cellular health and brain function—positioning them at the forefront of premium supplement manufacturing.
Usana Health Sciences
Usana Health Sciences, based in Utah, generates over $1 billion in annual revenue and sells nutritional supplements via a direct sales model in 24 countries . Their vertically integrated Salt Lake City manufacturing facility produces high-quality vitamins, minerals, and weight-management products under strict quality controls.
4. NutraPak USA
NutraPak USA, based in New Jersey, is a highly regarded contract manufacturer that supports softgels, tablets, capsules, powders, and liquids . Known for flexible private-label production and transparent communication, they meet varying business needs—from niche startups to large enterprises.
5. Cavendish Nutrition
Cavendish Nutrition, headquartered in New York, specializes in turnkey formulations and cGMP-compliant production of custom supplements . With over two decades of experience and FDA-inspected facilities, they excel in sports nutrition, immunity, and cognitive support formulas.
6. Brand International
Brand International offers a full suite of supplement manufacturing services—private label softgels, probiotics, sports nutrition, and pet health—from its FDA-inspected and cGMP-certified facilities . They are recognized for product versatility and high standards of quality.
7. HH Processors
HH Processors is a U.S.-based manufacturer with a fully-integrated 16,000 sq ft facility, known for vertically managed operations that streamline ingredients sourcing to production . Their expertise in nutritional and personal care products provides clients with consistent quality and supply reliability.
8. ENZ Pharmtech (Global Reach)
ENZ Pharmtech is a large-scale dietary supplement contract manufacturer with roots in the U.S. and Asia . They offer one-stop private-label services, including gummies, capsules, tablets, powders, drops, and gels. Their facilities feature ISO9001, ISO22000, HACCP, BRC, FDA, and GMP certifications, along with cleanrooms and pilot labs —making them a trusted global partner for brands seeking scalable, compliant production.
Summary Table
| Company | Core Offerings | Certifications & Facilities | Best For |
|---|---|---|---|
| Pharmavite | Multivitamins, gummy blends | FDA cGMP, NSP, USP; Gummy Center | Mass-market vitamins & custom blends |
| Elysium Health | Longevity & brain supplements | Premium benchmarks, research-first | Science-driven, niche health products |
| Usana | General & weight supplements | Direct sales, in-house production | High-quality, globally distributed nutrition |
| NutraPak USA | Softgels, tablets, powders | cGMP compliant NJ facility | Private label flexibility & small-to-large runs |
| Cavendish Nutrition | Turnkey formulas | FDA-inspected, high-quality labs | Custom solutions, sports & wellness brands |
| Brand International | Softgels, probiotics, pet health | FDA, cGMP certified | Broad format manufacturing |
| HH Processors | Powders, nutraceuticals, personal care | 16,000 sq ft vertically integrated | Full-service production & consistent supply |
| ENZ Pharmtech | Gummies, capsules, powders, gels, drops | ISO9001, ISO22000, HACCP, BRC, FDA, GMP | Global OEM/ODM turnkey solutions |